Immediately after the Masters in mid-April 2016, DeChambeau turned professional and signed a long-term agreement with Cobra-Puma Golf. He made his pro debut days later at the RBC Heritage in South Carolina and tied for fourth, earning over $259,000. The decision to turn professional meant the forfeiture of his exemptions to the U. S. Open at Oakmont and Open Championship at Royal Troon; he qualified his way into the U. S. Open, tied for fifteenth place for over $152,000, and improved his world ranking to 148. Despite the strong start, DeChambeau did not initially earn enough to qualify for a PGA Tour card, but had enough to earn entry into the Web. com Tour Finals. His first professional win was the DAP Championship which also earned him a PGA Tour Card for the 2017 PGA Tour. On July 16, 2017, DeChambeau earned his first PGA Tour victory by winning the John Deere Classic by a single stroke over Patrick Rodgers. He carded a round of 65 in the final round to win his maiden title in his 40th start on tour. The win coming the week before, gained DeChambeau a place in the 2017 Open Championship, where he missed the cut after rounds of 76–77 (+13). In 2017, Dechambeau gifted U. S. President Donald J. Trump golf clubs valued at $750.