Built by the eastern Roman emperor Justinian I as the Christian cathedral of Constantinople for the state church of the Roman Empire between 532 and 537, the church was then the world's largest interior space and among the first to employ a fully pendentive dome. It is considered the epitome of Byzantine architecture and is said to have "changed the history of architecture". The building was designed by the Greek geometers Isidore of Miletus and Anthemius of Tralles. The present Justinianic building was the third church of the same name to occupy the site, the prior one having been destroyed in the Nika riots. Being the episcopal see of the ecumenical patriarch of Constantinople, it remained the world's largest cathedral for nearly a thousand years, until Seville Cathedral was completed in 1520. Beginning with subsequent Byzantine architecture, Hagia Sophia became the paradigmatic Orthodox church form and its architectural style was emulated by Ottoman mosques a thousand years later. It has been described as "holding a unique position in the Christian world", and architectural and cultural icon of Byzantine and Eastern Orthodox civilization.